The gut microbiome regulates the psychomotor effects and context-dependent rewarding responses to cocaine

This study explores the microbiome's role in cocaine-induced psychomotor activation and context-dependent rewarding responses using germ-free (GF: mice raised without microorganisms) and antibiotic-treated (ABX: mice with depleted gut bacteria) models.

本研究借助无菌（GF：无微生物饲养的小鼠）与抗生素处理（ABX：肠道菌群耗竭的小鼠）模型，探究了微生物组（microbiome）在可卡因诱导的精神运动激活及情境依赖性奖赏应答中的作用。