MSI1 promotes the expression of the GBM stem cell marker CD44 by impairing miRNA-dependent degradation. [RNA-Seq II]
收藏干细胞与再生医学数据中心2022-02-20 更新2024-03-06 收录
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The stem cell marker Musashi1 (MSI1) is highly expressed during neurogenesis and in Glioblastoma (GBM). In cancer and non-malignant progenitor cells, MSI1 promotes self-renewal and impairs differentiation, involving the regulation of mRNA translation. However, a comprehensive understanding of MSI1âs role in promoting GBM-driving networks remains to be deciphered.
提供机构:
Martin Luther University Halle-Wittenberg
创建时间:
2022-02-20



