MYB Binding: Protein 1 A (MYBBP1A) is hemizygous in a majority of PDAC due to chromosome 17p deletion which also affects TP53. We generated isogenic homozygous and hemizygous MYBBP1A knockout cel
Pilocytic astrocytomas (PA) are the most common brain tumor in pediatric patients and can cause significant morbidity, including chronic neurological deficiencies. They are characterized by activating
Kaposi's sarcoma (KS), is an AIDS-associated neoplasm caused by the KS herpesvirus (KSHV/ HHV-8). KSHV-sarcomagenesis is the consequence of oncogenic viral gene expression as well as host genetic and
