RNA-Seq data from ZR75-1 cells. Homo sapiens

We report the transcription factor Six1 directly increases the expression of many glycolytic genes by performing RNA sequencing using Six1 stable knockdown ZR75-1 breast cancer cell line and control cell line. Overall design: Examination of ZR75-1 cells stably infected with lentivirus carrying Six1 shRNA or control shRNA

本研究通过使用稳定敲低Six1的ZR75-1乳腺癌细胞系及对照细胞系开展RNA测序（RNA sequencing）实验，证实转录因子Six1可直接上调诸多糖酵解基因的表达。整体实验设计：对经慢病毒（lentivirus）感染携带Six1短发夹RNA（short hairpin RNA，shRNA）或对照shRNA的稳定ZR75-1细胞进行检测。