Hurthle cell carcinoma - Not available, 65 - Tissue image [3300730069486781]

This is the histopathological image of THYROID GLAND tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 65Clinical description: A thyroid lobe measuring 5.5x4x4 cm. An ill-defined, beige tumor measuring approximately 4.4x2.8x2 cm was present on sectioning.Gender: Not availableDiagnosis:Classification: ICD-O_3.2Classification code: ADENOMAS AND ADENOCARCINOMASDiagnosis: Hurthle cell carcinomaResult of the histopathological examination: Hurtle cell carcinoma, widely invasive. Tumor confined to the thyroid gland removed completely. Features of angioinvasion in single blood vessels at the periphery of the tumor are present. IHC: calcitonin(-), synaptophysin (-/+), chromogranin A(-), TTF1(+), Ki67 10%. Mitotic figures: 1/10 HPF.Sample:Material: FFPECollecting method: Surgical specimenTopography: THYROID AND OTHER ENDOCRINE GLANDSOrgan: THYROID GLANDTissue: Thyroid, NOSType of staining: positive/HEStaining: Not applicableAntibody: Not applicableTechnology:Equipment: Pannoramic 250 3DHistechLens: 20xOrganization:Source: Medical University Gdańsk

本数据集为格但斯克医科大学（Medical University Gdańsk）获取并存储于ZMDL-GUMED的甲状腺组织样本的组织病理学图像。该样本图像采用Pannoramic 250 3DHistech玻片扫描仪拍摄（放大倍率20×），并以DICOM格式保存。患者、样本及诊断的详细信息如下：患者信息：年龄65岁；临床描述：甲状腺叶尺寸为5.5×4×4 cm，剖检可见一枚边界不清、呈米色的肿瘤，大小约4.4×2.8×2 cm；性别不详。诊断分类：依据ICD-O_3.2分类标准，分类编码对应腺瘤与腺癌（ADENOMAS AND ADENOCARCINOMAS）；最终诊断为Hurthle细胞癌（Hurthle cell carcinoma）。组织病理学检查结果：Hurthle细胞癌，呈广泛侵袭性；肿瘤完全切除且局限于切除的甲状腺组织内；肿瘤周边可见单支血管存在血管侵袭特征。免疫组化（IHC，Immunohistochemistry）结果：降钙素（calcitonin）阴性（-）、突触素（synaptophysin）阴性/弱阳性（-/+）、嗜铬粒蛋白A（chromogranin A）阴性（-）、甲状腺转录因子1（TTF1，Thyroid Transcription Factor 1）阳性（+），Ki67增殖指数为10%；核分裂象计数：1个/10高倍视野（HPF，High Power Field）。样本详情：样本材质为福尔马林固定石蜡包埋（FFPE，Formalin-Fixed Paraffin-Embedded）样本；采集方式为手术标本；解剖部位为甲状腺及其他内分泌腺（THYROID AND OTHER ENDOCRINE GLANDS）；所属器官为甲状腺（THYROID GLAND）；组织类型为甲状腺组织（未特指，NOS）；染色类型为阳性/苏木精-伊红（HE）染色；染色方案不适用；抗体不适用；成像技术参数：设备为Pannoramic 250 3DHistech，镜头放大倍率为20×；机构来源为格但斯克医科大学（Medical University Gdańsk）