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Structural effects of sequence context on lesion recognition by MutM

NIAID Data Ecosystem2026-05-02 收录

DNA损伤修复

序列上下文效应

数据链接：

https://www.rcsb.org/structure/3U6M 数据链接链接失效反馈

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资源简介：

Structural effects of sequence context on lesion recognition by MutM

序列上下文对MutM识别DNA损伤的结构效应

应用场景：

创建时间：

2024-11-27

DNA损伤修复

抗癌药物设计

Homologous recombination repair (HRR), a crucial approach in DNA damage repair, is an attractive target in cancer therapy and drug design. The Bloom syndrome protein (BLM) is a 3′–5′ DNA helicase that

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ChIP-seq mapping of KAT8 acetylatransferase at AsiSI-induced DNA double strand break sites

DNA损伤修复

表观遗传调控

C8orf33-proficient and deficient DIvA cells were treated with 4-hydroxy tamoxifen (4OHT) to induce DNA double strand breaks (DSB) at several loci within the human genome. following 4OHT treatment cell

NIAID Data Ecosystem20

Additional file 2 of Role of TDP2 in the repair of DNA damage induced by the radiomimetic drug Bleomycin

DNA损伤修复

药物诱导DNA损伤

Supplementary Material 2.

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Summarized fold change values by microarray results of the selected 9 CPD-dependent genes.

微阵列基因表达

DNA损伤修复

active PL: samples containing active CPD-photolyase, inactive PL: samples containing inactive CPD-photolyase.Summarized fold change values by microarray results of the selected 9 CPD-dependent genes.

Figshare2015-12-03 更新30

CRYSTAL STRUCTURE OF HUMAN DNA POLYMERASE ETA INSERTING dAMPNPP ACROSS A DNA TEMPLATE CONTAINING 1,N6-ETHENODEOXYADENOSINE LESION

DNA损伤修复

酶晶体结构

CRYSTAL STRUCTURE OF HUMAN DNA POLYMERASE ETA INSERTING dAMPNPP ACROSS A DNA TEMPLATE CONTAINING 1,N6-ETHENODEOXYADENOSINE LESION

NIAID Data Ecosystem10