Multiparametric domain insertional profiling of Adeno-Associated Virus VP1

We determine multiple AAV fitness phenotypes upon insertion of the FLAG peptide tag as well as several large, structured protein domains into most positions of Adeno-Associated Virus capsid protein VP1.我们将FLAG肽标签及数个大型结构化蛋白质结构域插入至腺相关病毒（Adeno-Associated Virus）VP1衣壳蛋白的绝大多数位点，以此确定该病毒的多种适配性表型。