ACCURACY OF OSCILLOMETRIC (PETMAPTM) AND DOPPLER METHODS TO INDIRECT MEASUREMENT OF BLOOD PRESSURE IN LAMBS

Abstract Neonatal physiology has peculiarities inherent to the age group. The objective of this study was to monitor the systemic arterial pressure in lambs during neonatal period. We used 20 Ile de France lambs, from birth and at 7, 14, 21, 28 and 35 days of life. The following parameters were analyzed: heart rate (HR), systolic (SBP), diastolic (DBP), and average blood pressure (ABP) by oscillometric method petMAPTM, and SBP with Doppler. Invasive pressure validated indirect methods with the average 101.52 ± 12.04 mmHg. The averages with petMAPTM were as follows: HR (156.38 ± 37.46 bpm); DBP (63.80 ± 11.14 mmHg); ABP (81.58 ± 11.83 mmHg); SBP (112.48 ± 15.68 mmHg) and SBP by Dobler (90.27 ± 12.11 mmHg). There was significant difference in HR and blood pressure among the moments. Indirect methods differ between each other in 12.30 mmHg (overestimation of 11%). Comparing with the invasive methods, both overestimated values of 4% and 16% in PAS, respectively, for Doppler and petMAPTM. The results showed that the Doppler method has established a good relationship with the invasive one being useful for gauging the SBP. The oscillometric method requires larger studies to be used in small ruminants.

摘要 新生羔羊生理学具有该年龄组特有的生理特质。本研究旨在监测新生羔羊新生儿期的体动脉压。研究共纳入20只法兰西岛（Ile de France）羔羊，分别于出生当日及出生后7、14、21、28、35日龄开展检测。本研究分析的参数包括：采用示波法petMAPTM设备检测心率（heart rate, HR）、收缩压（systolic blood pressure, SBP）、舒张压（diastolic blood pressure, DBP）及平均动脉压（average blood pressure, ABP），并采用多普勒法检测收缩压（SBP）。以有创血压作为金标准对两种间接检测方法进行验证，有创血压的均值为101.52±12.04 mmHg。采用petMAPTM设备检测的各项指标均值如下：HR为156.38±37.46次/分（bpm）；DBP为63.80±11.14 mmHg；ABP为81.58±11.83 mmHg；SBP为112.48±15.68 mmHg；多普勒法检测的SBP均值为90.27±12.11 mmHg。不同日龄阶段的心率与血压均存在显著差异。两种间接检测方法间的均值差值为12.30 mmHg，相对高估幅度达11%。与有创血压检测结果相比，多普勒法与petMAPTM设备分别高估了4%与16%的收缩压数值。研究结果表明，多普勒法检测结果与有创血压检测结果具有良好的相关性，可有效用于收缩压的测定。示波法在小型反刍动物中的应用仍需开展更大规模的研究予以验证。