Response of C. jejuni to various environmental conditions

Campylobacter jejuni is the leading cause of foodborne human gastroenteritis in the developed world. Infections are largely acquired from poultry produced for human consumption and poor food handling is thus a major risk factor. In this study, C. jejuni were exposed to growth in a number of enviornmental conditions representative of the human gastrointestinal tract, including 0.1% deoxycholate (DOC), under iron limitation (induced by 1 mM deferroxamine, in the presence of chicken 'juice' or 'exudate (the thaw water of frozen commerical chicken products) and in the presence of mammalian mucin.

空肠弯曲菌（Campylobacter jejuni）是发达国家食源性人类胃肠炎的首要致病菌。其感染大多源于供人类食用的家禽制品，因此食品处理不当是主要的感染风险因素。本研究中，研究人员将空肠弯曲菌置于多种模拟人类胃肠道的环境条件下培养，包括0.1%脱氧胆酸盐（deoxycholate, DOC）、铁限制培养条件（由1 mM去铁胺诱导，同时添加鸡汁或鸡渗出液——即冷冻商业鸡肉产品的解冻水），以及添加哺乳动物黏蛋白的培养环境。