Subgroup analysis of association between <i>XPD</i> haplotype and overall survival.

NOTE: ECOG PS, Eastern Cooperative Oncology Group performance status; TNM, tumor-node-metastasis; MST, median survival time; HR, hazards ratio; BFDP, Bayesian false-discovery probability. Bold figures are those that remained noteworthy at the 0.8 BFDP level, suggesting true associations. †Haplotype was composed in order of Asp312Asn, Asp711Asp and Lys751Gln; GCA was the most common haplotype. ‡Stratified tests was estimated by Multivariate Cox proportional hazards models, with adjustment of patient characteristics with P<0.05 in univariate analysis (performance status, clinical stage, and type of treatment regimens).注：ECOG PS（东部肿瘤协作组体能状态评分，Eastern Cooperative Oncology Group performance status）；TNM（肿瘤-淋巴结-转移分期系统，tumor-node-metastasis）；MST（中位生存期，median survival time）；HR（风险比，hazards ratio）；BFDP（贝叶斯错误发现概率，Bayesian false-discovery probability）。加粗数值为在0.8的BFDP阈值下仍具有统计学意义的结果，提示存在真实关联。 † 单倍型按Asp312Asn、Asp711Asp及Lys751Gln的顺序组成；GCA为最常见的单倍型。 ‡ 分层检验采用多变量Cox比例风险模型估算，校正了单变量分析中P<0.05的患者临床特征：体能状态、临床分期及治疗方案类型。