five

Supplementary Table S6.2.

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Associated patient data and antibiotic susceptibility data of all viable Neisseria gonorrhoeae isolates collected in 2019 in Portugal on behalf of the PTGonoNET. MSM – Men who have sex with men; MSMW – Men who have sex with men and women; AZM – Azithromycin; CIP – Ciprofloxacin; CFM – Cefixime; CRO – Ceftriaxone; PEN – Penicillin; RI – Rifampicin; SPT – Spectinomycin; TET – Tetracycline; CEF – cephalosporins; GEN – Gentamicin; β-LACT – β-lactamase; NUT – Nomenclature of Territorial Units for Statistics; MIC – Minimum inhibitory concentration; RP – Resistance phenotype. *For this study, if the patient’s region of residence was not available, the geographic region of the reporting laboratory was attributed to the isolate. **Due to the lack of an established breakpoint, gentamicin susceptibility was classified for analysis purposes based on interpretive results from previous studies: as susceptible when MIC ≤ 4, and resistant when MIC > 16 mg/L, according to Boiko et al., 2019; APMIS, 127(7):503-509 (doi:10.1111/apm.12948) and Brown et al., 2010; Sex Transm Dis., 37(3):169-172 (doi:10.1097/OLQ.0b013e3181bf575c).

本数据集包含2019年葡萄牙代表PTGonoNET项目收集的所有存活淋病奈瑟菌(Neisseria gonorrhoeae)分离株的关联患者数据与抗生素敏感性数据。其中,MSM指男男性行为者(Men who have sex with men);MSMW指男与男性和女性发生性行为者(Men who have sex with men and women);AZM为阿奇霉素(Azithromycin);CIP为环丙沙星(Ciprofloxacin);CFM为头孢克肟(Cefixime);CRO为头孢曲松(Ceftriaxone);PEN为青霉素(Penicillin);RI为利福平(Rifampicin);SPT为壮观霉素(Spectinomycin);TET为四环素(Tetracycline);CEF为头孢菌素类(cephalosporins);GEN为庆大霉素(Gentamicin);β-LACT为β-内酰胺酶(β-lactamase);NUT为统计区域命名法则(Nomenclature of Territorial Units for Statistics);MIC为最低抑菌浓度(Minimum inhibitory concentration);RP为耐药表型(Resistance phenotype)。 *本研究中,若患者的常住区域信息缺失,则以报告该分离株的实验室所在地理区域替代其归属区域。 **由于暂无公认的药敏折点,本分析参照既往研究的判读标准对庆大霉素敏感性进行分类:参照Boiko等人2019年发表于APMIS, 127(7):503-509(DOI:10.1111/apm.12948)及Brown等人2010年发表于Sex Transm Dis., 37(3):169-172(DOI:10.1097/OLQ.0b013e3181bf575c)的研究结果,当最低抑菌浓度(MIC)≤4 mg/L时判定为敏感,MIC>16 mg/L时判定为耐药。
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2020-11-04
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