DataSheet1_Positive vaccine beliefs linked to reduced mental stress in healthcare professionals during COVID-19: a retrospective study.pdf

Background and aimThe COVID-19 pandemic has led to a significant adverse effect on the mental health of healthcare professionals. This study aims to assess the effects of the prolonged pandemic on burnout and mood disorders and to evaluate the influence of positive vaccination beliefs on these factors at a medical center during the extended COVID-19 pandemic.
MethodsThis retrospective study analyzed the results of an online questionnaire survey including burnout status and mood disorders from 2020 to 2022. The factors related to mood moderate/severe disorders and the impact of the positive vaccine belief were also explored.
ResultsThe initial analysis revealed that healthcare professionals continued to experience significant levels of personal and work-related burnout, along with mood disorders. However, the scores and the percentage of moderate to severe burnout gradually decreased. Notably, the percentage of individuals with moderate to severe mood disorders also gradually declined (2020: 13.4%, 2021: 12.3%, 2022: 11.1%). The number of participants who need professional interventions decreased from 56.2% in 2020 to 45.9% in 2021, and 46% in 2022. Multivariate analysis revealed a positive vaccine belief was associated with a lower risk of moderate/severe mood disorders, with odd ratios (OR) and 95% confidence intervals (95% CI) of 0.38 (0.28 – 0.52) and 0.41 (0.30 – 0.52) in the 2021 and 2022 cohorts, respectively. Further investigation revealed that age over 50 was linked to a positive vaccine belief in 2021 and 2022. Within the 2022 cohort, working as nurses was identified as the independent factor associated with a less positive belief, with the OR and 95% CI of 0.49 (0.27 – 0.90).
ConclusionThe findings of the present study suggest burnout and mood disorders are still significant during the pandemic. A positive vaccine belief may mitigate pandemic-related mental distress. Further interventions to enhance the belief combined with other supporting measures are important in a long fight against the pandemic.

研究背景与目的
新型冠状病毒肺炎（COVID-19）疫情对医护人员的心理健康造成了显著的不良影响。本研究旨在评估新冠疫情迁延期间，某医疗中心内医护人员的职业倦怠（Burnout）与心境障碍发病情况，并探究积极疫苗接种信念对上述两类心理健康问题的影响。

研究方法
本项回顾性研究分析了2020年至2022年间开展的线上问卷调查结果，问卷内容涵盖医护人员的职业倦怠状况与心境障碍表现。同时本研究还探讨了与中度/重度心境障碍相关的影响因素，以及积极疫苗接种信念的作用效应。

研究结果
初步分析结果显示，医护人员仍存在较高水平的职业倦怠（包括个体层面与工作相关的倦怠）及心境障碍问题。但职业倦怠的评分及中度至重度职业倦怠的占比呈逐步下降趋势。值得注意的是，中度至重度心境障碍的患者占比同样逐步降低（2020年：13.4%，2021年：12.3%，2022年：11.1%）。需要专业心理干预的受试者占比从2020年的56.2%降至2021年的45.9%，2022年为46%。多因素分析结果表明，积极的疫苗接种信念与中度/重度心境障碍的发病风险降低相关：2021年队列的比值比（Odds Ratio, OR）及95%置信区间（95% Confidence Interval, 95% CI）为0.38（0.28~0.52），2022年队列则为0.41（0.30~0.52）。进一步分析显示，2021年与2022年队列中，年龄超过50岁与积极疫苗接种信念呈正相关。在2022年队列中，护士职业是与疫苗接种信念偏弱相关的独立影响因素，其OR值及95%CI为0.49（0.27~0.90）。

研究结论
本研究结果表明，新冠疫情迁延期间，医护人员的职业倦怠与心境障碍问题仍较为突出。积极的疫苗接种信念或可缓解疫情相关的心理困扰。在长期抗击疫情的过程中，通过干预手段强化医护人员的疫苗接种信念，并辅以其他支持性措施，具有重要意义。