Additional file 1 of Assessment of genetic susceptibility to multiple primary cancers through whole-exome sequencing in two large multi-ancestry studies

Additional file 1: Table S1. Cancer Site Coding Following SEER and WHO Guidelines. Table S2. Unique Cancer Pairs and Sample Counts in the Kaiser Permanente Research Bank and UK Biobank. Table S3. Sample Counts for Shared Index Cancers Across All Diagnoses in the Kaiser Permanente Research Bank and UK Biobank. Table S4. Single Variant Association Summary Statistics for Multiple Primary Cancers Combined or Grouped by Organ Site. Table S5. Gene-Based Association Summary Statistics for Multiple Primary Cancers Combined or Grouped by Organ Site. Table S6. Single Variant Burden in Individuals with Multiple Versus Single Cancers. Table S7. Gene-Based Burden in Individuals with Multiple Versus Single Cancers.附加文件1：表S1。遵循美国监测、流行病学与最终结果数据库（Surveillance, Epidemiology, and End Results Program，SEER）及世界卫生组织（World Health Organization，WHO）指南的癌症部位编码规范。表S2：凯萨永久研究银行（Kaiser Permanente Research Bank）与英国生物银行（UK Biobank）中的独特癌症配对及样本量。表S3：凯萨永久研究银行与英国生物银行中，全诊断范畴内共有索引癌症的样本量。表S4：按器官部位合并或分组的多重原发癌症的单变异关联汇总统计量。表S5：按器官部位合并或分组的多重原发癌症的基于基因的关联汇总统计量。表S6：多发癌症与单发癌症患者的单变异负荷。表S7：多发癌症与单发癌症患者的基于基因的负荷。