Fragment-based Discovery of Protein-Protein Interaction Inhibitors of Replication Protein A

Fragment-based Discovery of Protein-Protein Interaction Inhibitors of Replication Protein A Descriptor: Replication protein A 70 kDa DNA-binding subunit, {[5-(3-chloro-1-benzothiophen-2-yl)-4-phenyl-4H-1,2,4-triazol-3-yl]sulfanyl}acetic acid Authors: Feldkamp, M.D, Patrone, J.D, Kennedy, J.P, Frank, A.O, Vangamudi, B, Pelz, N.F, Rossanese, O.W, Waterson, A.G, Fesik, S.W, Chazin, W.J. Deposit date: 2012-12-21 Release date: 2013-08-14 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Discovery of Protein-Protein Interaction Inhibitors of Replication Protein A. ACS MED.CHEM.LETT., 4, 2013基于片段的复制蛋白A（Replication Protein A）蛋白相互作用抑制剂发现 描述：复制蛋白A 70 kDa DNA结合亚基，{[5-(3-氯-1-苯并噻吩-2-基)-4-苯基-4H-1,2,4-三唑-3-基]硫基}乙酸 作者：Feldkamp, M.D、Patrone, J.D、Kennedy, J.P、Frank, A.O、Vangamudi, B、Pelz, N.F、Rossanese, O.W、Waterson, A.G、Fesik, S.W、Chazin, W.J. 提交日期：2012-12-21 发布日期：2013-08-14 最后修改日期：2023-09-20 实验方法：X射线衍射（1.7 Å） 引用文献：《复制蛋白A蛋白相互作用抑制剂的发现》，ACS 药物化学快报（ACS MED.CHEM.LETT.），第4卷，2013年