Lactate mediated epigenetic reprogramming during cancer associated fibroblast formation. Lactate mediated epigenetic reprogramming during cancer associated fibroblast formation

We report oxidative bisulfite analysis of whole genome methylation of mesenchymal stem cells (MSCs) and Cancer associated fibroblasts (CAFs) Overall design: Examination of 5hmC in MSCs and CAFs

本研究报道了间充质干细胞（mesenchymal stem cells, MSCs）与癌相关成纤维细胞（Cancer associated fibroblasts, CAFs）的全基因组甲基化氧化亚硫酸氢盐分析（oxidative bisulfite analysis）。实验设计：检测间充质干细胞与癌相关成纤维细胞中的5-羟甲基胞嘧啶（5hmC）。