Characterization_and_genome_annotation_of_natural_pathogens_of_C__elegans. Characterization_and_genome_annotation_of_natural_pathogens_of_C__elegans

We have identified four new pathogens of C. elegans isolated from their natural environment of decaying apples in France that have unique effects on C. elegans physiology. As part of this study we will sequence and annotate the genomes of these as-yet-uncharacterized bacterial species as well as determine the molecular factors regulating C. elegans response to these various pathogens using a variety of genetics, biochemical, and systems biology approaches. This data is part of a pre-publication release. For information on the proper use of pre-publication data shared by the Wellcome Trust Sanger Institute (including details of any publication moratoria), please see http://www.sanger.ac.uk/datasharing/我们从法国腐烂苹果的自然生境中分离得到四株全新的秀丽隐杆线虫（Caenorhabditis elegans）致病菌，这些致病菌对秀丽隐杆线虫的生理机能具有独特影响。作为本研究的组成部分，我们将对这些尚未被表征的细菌物种的基因组进行测序与注释，并借助遗传学、生物化学以及系统生物学等多种研究手段，解析调控秀丽隐杆线虫对上述多种致病菌产生应答反应的分子因子。本数据集属于预发布数据。如需了解威康桑格研究所（Wellcome Trust Sanger Institute）共享的预发布数据的规范使用方式（包括各类发表禁运条款的细节），请访问http://www.sanger.ac.uk/datasharing/