WGBS and RNA-Seq analysis reveal the regulatory role of DNA methylation in pumpkin (Cucurbita moschata) resistance to Phytophthora xanthii

We analyzed the transcription and methylation levels of the entire genome to understand its response to PM stress. And explored the relationship between the transcription level and methylation level of some genes. Reveal whether DNA methylation is directly involved in the regulation of pumpkin PM resistance, and further reveal the molecular mechanism of pumpkin PM resistance.

本研究通过分析全基因组的转录水平与甲基化水平，以解析其对白粉病(Powdery Mildew, PM)胁迫的响应；同时探究了部分基因的转录水平与甲基化水平之间的关联，旨在明确DNA甲基化(DNA methylation)是否直接参与调控南瓜白粉病抗性，并进一步揭示南瓜白粉病抗性的分子机制。