Virome of tonsils from pigs

The porcine respiratory disease complex (PRDC) is a multifactorial disease complex that can be influenced by a number of different microorganisms as well as by non-infectious factors such as management and the environment. It is generally believed that the interaction between different infectious agents plays an important role in PRDC. Therefore, we used high-throughput sequencing combined with viral metagenomics to characterise the viral community of tonsil samples from pigs coming from a conventional herd attended with lesions in the respiratory tract at slaughter. In parallel, samples from specific pathogen-free pigs were analysed.

猪呼吸道疾病复合征（porcine respiratory disease complex, PRDC）是一类多因素性疾病复合体，可受多种不同微生物以及饲养管理、环境等非感染性因素影响。目前学界普遍认为，不同感染因子之间的相互作用在PRDC的发生发展中发挥重要作用。为此，本研究采用高通量测序（high-throughput sequencing）结合病毒宏基因组学（viral metagenomics）技术，对屠宰场中来自存在呼吸道病变的常规饲养猪群的猪扁桃体样本的病毒群落进行了表征；同时，并行分析了无特定病原体（specific pathogen-free, SPF）猪的相关样本。