Treatment and research lines for the patient with COVID-19. What do we have and where are we going?

ABSTRACT Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) represents the most significant global public health crisis of this generation. From the beginning of the pandemic, several publications and on-line resources about different treatment lines have been done, and development effort in response to the COVID-19 pandemic to investigate potential therapies is unprecedented. Unfortunately, until now, there is not enough evidence to recommend any specific anti-COVID19 treatment. Randomized clinical trials and high-quality evidence, even in the middle of a pandemic, are needed. We provide a review of the latest published literature on the therapeutic strategies and current investigational lines for SARS-CoV-2.摘要：由严重急性呼吸综合征冠状病毒2（SARS-CoV-2）引发的2019冠状病毒病（COVID-19），是当代最严峻的全球性公共卫生危机。自新冠大流行伊始，学界已发布诸多针对不同治疗方案的学术成果与在线资源，为研究潜在疗法以应对COVID-19大流行而投入的研发力度前所未有。遗憾的是，截至目前尚无足够证据可推荐任何特定的抗COVID-19治疗方案。即便在大流行期间，仍亟需开展随机临床试验并获取高质量证据。本研究针对严重急性呼吸综合征冠状病毒2的治疗策略与当前在研方向，综述了最新发表的相关文献。