SpCas9 bound to 6 nucleotide complementary DNA substrate

NIAID Data Ecosystem2026-05-02 收录

CRISPR-Cas9

DNA底物结合机制

数据链接：

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SpCas9 bound to 6 nucleotide complementary DNA substrate

与6核苷酸互补DNA底物结合的化脓链球菌Cas9（SpCas9）

创建时间：

2025-07-09

HT29 reference dataset

CRISPR-Cas9

癌细胞研究

We provide a dataset that can be used (through a dedicated R package and metrics) for the assessment of novel experimental pipelines upon the execution of a single calibration viability screen of the

DataCite Commons2025-06-01 更新430

大型经济海藻条斑紫菜的基因编辑将有利于其发展为模式海藻

基因编辑

CRISPR-Cas9

本数据包含条斑紫菜基因编辑系统开发过程中的载体构建测序结果、GUS报告基因表达活性、阳性藻株筛选胶图、靶位点测序峰图、gRNA和Cas9表达量等方面的数据。

国家海洋科学数据中心2025-12-22 更新50

The safety of highly stable Cas9 in mice

CRISPR-Cas9

基因编辑动物

Twenty-four male C57BL/6 mice (5 weeks old) were randomly divided into three groups (NC, Cas9, and HSCas9 groups). NC group were hydrodynamically injected with the plasmid pBB4.5-1.3HBV, PX458-Cas9, a

NIAID Data Ecosystem30

A Type II-B Cas9 nuclease with no detectable off-targets and reduced chromosomal translocations in vivo.

CRISPR-Cas9

基因治疗安全性

Streptococcus pyogenes Cas9 (SpCas9) and derived enzymes are widely used as components of CRISPR-Cas9 genome editing and engineering platforms. However, they exhibit promiscuous nuclease activity that

NIAID Data Ecosystem60

CRISPR-Cas9 knockout screens using the miRNA-targeting lentiG-miR library

CRISPR-Cas9

miRNA功能研究

The data includes NGS data analyses from CRISPR-Cas9 knockout screens for 47 human cancer cell lines, performed with PoolQ (v2.2.0). This output includes raw read counts of sgRNAs and corresponding qu

Figshare2024-04-25 更新40

SpCas9 bound to 6 nucleotide complementary DNA substrate

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