Functional reprogramming of neutrophils within tumors by hypoxia-driven histone lactylation [RNA-seq]

We used bulk RNAseq to study the mechanism underlying the functional reprogramming in brain tumors. FACS-sorted neutrophils from in vitro cultures and mouse brain tumors本研究采用批量RNA测序（bulk RNAseq）技术，探究脑肿瘤功能重编程的潜在机制。实验所用样本为经荧光激活细胞分选（FACS）获取的中性粒细胞，分别来源于体外培养体系与小鼠脑肿瘤组织。