We extend the boundaries of linkage mapping by genotyping a dense marker set on a large number of yeast segregants generated from a cross between two diverse yeast strains sk1 and s96. From our whole
File S1 contains supplementary materials and methods. Table S1 contains details about the yeast strains used in this study. Table S2 contains the plasmids used in this study. Table S3 contains oligonu
Ribosome profiling and RNA sequencing was performed on U2OS cells, either control or overexpressing myc. Overall design: 2 biological replicates of each condition.
Exogenous double-strand breaks (DSBs) induce a DNA damage response during mitosis as well as meiosis. The DNA damage response is mediated by a cascade involving Mec1/Tel1 (ATR/ATM) and Rad53 (Chk2) ki