Comparison of static histomorphometric trabecular bone parameters at the secondary spongiosa of 4-week-old female OA-Tg mice with age- and sex-matched WT littermates (mean ± SEM).*

*Measurments were performed at a site that was 300 µm away from the growth plate.**N.S. = Not significant.***% (BV/TV), trabecular area per total tissue area in percentage; Total OC#, total number of TRAP positive multinucleated osteoclasts; OC#.PM, number of TRAP positive osteoclasts per bone surface length; TRAP.PM, TRAP-stained bone surface per total tissue area; Tb.N, trabecular number; Tb.Th, trabecular thickness; and Tb.Sp, trabecular spacing.