Comparison of static histomorphometric trabecular bone parameters at the secondary spongiosa of 4-week-old female OA-Tg mice with age- and sex-matched WT littermates (mean ± SEM).*

*Measurments were performed at a site that was 300 µm away from the growth plate.**N.S. = Not significant.***% (BV/TV), trabecular area per total tissue area in percentage; Total OC#, total number of TRAP positive multinucleated osteoclasts; OC#.PM, number of TRAP positive osteoclasts per bone surface length; TRAP.PM, TRAP-stained bone surface per total tissue area; Tb.N, trabecular number; Tb.Th, trabecular thickness; and Tb.Sp, trabecular spacing.所有测量均在距生长板（growth plate）300 µm的位点进行。*N.S. = 无统计学显著性（Not significant）。* 其中，% (BV/TV，骨体积/总组织体积) 代表骨小梁面积占总组织面积的百分比；Total OC# 为抗酒石酸酸性磷酸酶（TRAP，Tartrate-Resistant Acid Phosphatase）阳性多核破骨细胞总数；OC#.PM 为每单位骨表面长度上的TRAP阳性破骨细胞数；TRAP.PM 指TRAP染色阳性骨表面占总组织面积的占比；Tb.N 为骨小梁数量；Tb.Th 为骨小梁厚度；Tb.Sp 为骨小梁间距。