Data Set.sav

The study was approved by the local ethic committee of Ben Arous hospital, Tunisia. Written consent for participation was obtained from each patient. Data collection was conducted in compliance with Tunisian laws regarding personal data protection. Statistical analysis was performed according to the intention-to-treat principle. Differences in the baseline characteristics and the primary and secondary outcome measures between the groups were compared with the chi-squared test for nominal variables, the independent Student’s t-test for continuous variables with normal distributions, and the nonparametric Mann-Whitney U test for continuous variables with skewed distributions. To address risk factors involved in SSI development other than suture type, a bivariate analysis was first conducted on all independent variables. Any variable with a statistically significant response, or very close to it (p <0.10), was considered a potential confounding factor. A multivariate logistic regression model, which considered the impact of all possible confounding factors identified in the bivariate analysis, was used to measure the adjusted effect of suture type on the development of SSI. To compare wound healing disturbances an univariate analysis was conducted. A p-value < 0.05 (two-sided) was considered to be significant.

本研究已获得突尼斯本阿鲁斯医院当地伦理委员会的批准。所有患者均签署了参与本研究的书面知情同意书。数据采集工作严格遵循突尼斯有关个人数据保护的法律法规。统计分析按照意向性治疗（intention-to-treat）原则开展。对两组患者的基线特征、主要及次要结局指标进行组间比较：名义变量采用卡方检验，符合正态分布的连续变量采用独立样本t检验，偏态分布的连续变量采用非参数曼-惠特尼U（Mann-Whitney U）检验。为探究除缝合类型外与手术部位感染（SSI, surgical site infection）发生相关的危险因素，本研究首先对所有自变量进行双变量分析。将P值<0.10或接近该阈值的变量视为潜在混杂因素。随后构建多因素logistic回归模型，纳入双变量分析中识别出的全部潜在混杂因素，以评估缝合类型对手术部位感染发生的校正后效应。针对伤口愈合异常情况的比较采用单变量分析。以双侧P值<0.05作为差异具有统计学意义的判定标准。