Cell-level measurements, lineage annotations and clinical metadata for "Robust multicellular programs dissect the complex tumor microenvironment and track disease progression in colorectal cancer"

Cell-level measurements, lineage annotations and clinical metadata for "Robust multicellular programs dissect the complex tumor microenvironment and track disease progression in colorectal cancer" Preprint: https://doi.org/10.48550/arXiv.2510.05083Code: https://doi.org/10.5281/zenodo.17186802 Description: cell_table.csv: intensity measured per channel and per cell, and cell location and shape descriptors, after artefact filtering (plain text CSV). Use the column fov to map it to the metadata. adata_consensus_cell_types.h5ad: cell-level measurements including cell type annotation (AnnData format). Use obs['fov'] to map it to the metadata. summary_clinical_data_modified.csv: clinical annotation per sample (plain text CSV). Use the column TMA Localisation to map it to the measurements. These files are proposed as entry points in reproducing or expanding our analyses. See the repository linked for the details of how the data is processed, and the preprint for scientific context. Multiplexed images and segmentation masks will be provided separately (BioImage Archive).本数据集对应论文《稳健的多细胞程序解析结直肠癌复杂肿瘤微环境并追踪疾病进展》，包含细胞级测量数据、谱系注释与临床元数据。 预印本：https://doi.org/10.48550/arXiv.2510.05083 代码：https://doi.org/10.5281/zenodo.17186802 数据说明： cell_table.csv：经伪影过滤后，各通道单细胞强度测量值，以及细胞定位与形态学描述符，文件格式为纯文本CSV。可通过fov列与元数据完成关联匹配。 adata_consensus_cell_types.h5ad：包含细胞类型注释的细胞级测量数据集，采用AnnData格式存储。可通过obs['fov']列与元数据完成关联匹配。 summary_clinical_data_modified.csv：单样本临床注释信息，文件格式为纯文本CSV。可通过TMA Localisation列与测量数据集完成关联匹配。 上述文件可作为复现或拓展本研究分析的核心切入点。数据处理细节与完整分析流程请参阅关联代码仓库，研究科学背景请查阅该预印本。多重成像图像与细胞分割掩码将通过BioImage Archive另行发布。