Challenge protocol time table.

Protocols to assess the ability of M. catarrhalis to induce OM in RSV-compromised juvenile chinchillas. For both protocols, nasopharyngeal mucosae, Eustachian tubes and middle ear mucosae were collected for culture at the time of sacrifice. Bullar washes were performed upon bisection of the bullae to recover planktonic M. catarrhalis.评估卡他莫拉菌（M. catarrhalis）在呼吸道合胞病毒（RSV）感染的幼年毛丝鼠中诱发中耳炎（OM）能力的实验方案。两种实验方案均在实验动物安乐死后，采集鼻咽黏膜、咽鼓管及中耳黏膜用于微生物培养。通过剖开鼓室实施鼓室灌洗，以回收浮游态卡他莫拉菌。