Ex Vivo Lung Perfusion as a Human Platform for Preclinical Small Molecule Testing

We report mRNA expression from human lung homogenate samples taken during Ex Vivo Lung Perfusion during an acute challenge with LPS and an intervention with the small molecule BC1215 Examination of tissue gene expression changes in response to LPS and the effect of BC 1215 on this LPS response本研究报道了在急性脂多糖（Lipopolysaccharide, LPS）刺激并经小分子化合物BC1215干预的离体肺灌注（Ex Vivo Lung Perfusion）过程中获取的人肺匀浆样本的mRNA表达谱；本数据集旨在分析组织基因表达对LPS刺激的应答变化，以及BC1215对该LPS介导应答的调控效应。