Tenoxicam (TNX) belongs to the oxicam family of drugs popularly known as nonsteroidal anti-inflammatory drugs (NSAIDs). Its therapeutic action as a drug is limited by poor aqueous solubility (14 mg/L)
Cocrystallization of an antifungal drug, griseofulvin (GF), with an artificial sweetener, acesulfame (Ace-H), resulted in a cocrystal monohydrate with GF and Ace-H in a 2:1 stoichiometric ratio. The c
Mechanochemistry is now regularly used to prepare multi-component molecular crystals for drug development and other applications. Mechanochemcial reactions enable cocrystal formation under mild condit
The reliability of solvent drop grinding (SDG), also referred to as liquid assisted grinding, wet cogrinding, or mechanochemistry, to facilitate cocrystal formation is addressed with a series of model
An anticancer drug, lenalidomide, has low oral bioavailability (below 33%) due to its poor solubility in water. To improve its solubility, three cocrystals of lenalidomide with urea (1) and 3,5-dihydr
