Microarray analysis of the effects of a γ-tocopherol-rich mixture of tocopherols on global gene expression in the prostates of TRAMP mice

We used whole mouse genome microarrays to the effects of γ-TmT on global gene expression in the prostate TRAMP and age-matched C57BL/6 mice were administered either 600 mg/kg of γ-TmT or a control vehicle via oral gavage. Twelve hours after dosing, prostate tissues were collected for RNA extraction.

我们采用全小鼠基因组微阵列（whole mouse genome microarrays）分析γ-TmT对前列腺TRAMP小鼠及同月龄C57BL/6小鼠全局基因表达的影响：通过口服灌胃方式为两组小鼠分别给予600 mg/kg的γ-TmT或对照溶剂。给药12小时后，采集前列腺组织用于RNA提取。