Hayer2005_simple_AMPAR_traff_model2

This is a highly simplified model of the AMPAR trafficking cycle that exhibits bistability. It is model 2 from Hayer and Bhalla, PLoS 2005. Its main purpose it to illustrate how the bistability arises. This model originates from BioModels Database: A Database of Annotated Published Models (http://www.ebi.ac.uk/biomodels/). It is copyright (c) 2005-2011 The BioModels.net Team. To the extent possible under law, all copyright and related or neighbouring rights to this encoded model have been dedicated to the public domain worldwide. Please refer to CC0 Public Domain Dedication for more information. In summary, you are entitled to use this encoded model in absolutely any manner you deem suitable, verbatim, or with modification, alone or embedded it in a larger context, redistribute it, commercially or not, in a restricted way or not.. To cite BioModels Database, please use: Li C, Donizelli M, Rodriguez N, Dharuri H, Endler L, Chelliah V, Li L, He E, Henry A, Stefan MI, Snoep JL, Hucka M, Le Novère N, Laibe C (2010) BioModels Database: An enhanced, curated and annotated resource for published quantitative kinetic models. BMC Syst Biol., 4:92.本模型为一款高度简化的AMPA受体（AMPAR）转运循环模型，具备双稳态特性。该模型是Hayer与Bhalla于2005年发表于PLoS的模型2，其核心目的在于阐释双稳态特性的产生机制。 本模型源自BioModels数据库——一款经注释的已发表模型数据库（网址：http://www.ebi.ac.uk/biomodels/），版权归属于2005-2011年的BioModels.net团队。 在法律允许的最大范围内，本编码模型的全部版权及相关邻接权利已被奉献至全球公共领域。如需了解更多信息，请参阅CC0公共领域贡献声明。 简言之，您可自由以任何合适方式使用本编码模型：可原样复制、修改后使用，可单独使用或将其嵌入更大的研究框架中；可进行再分发，无论是否用于商业用途、是否存在使用限制。 若需引用BioModels数据库，请采用如下著录格式：Li C, Donizelli M, Rodriguez N, Dharuri H, Endler L, Chelliah V, Li L, He E, Henry A, Stefan MI, Snoep JL, Hucka M, Le Novère N, Laibe C（2010）BioModels数据库：面向已发表定量动力学模型的增强型、经审校与注释的资源。《BMC系统生物学》，4:92。