Expression data from multiple myeloma cells treated with arsenic. Homo sapiens

We used microarrays to examine changes in gene expression in multiple myeloma cell lines following treatment with arsenic trioxide and darinaparsin Keywords: Time course Overall design: Four multiple myeloma cell lines (U266, MM.1s, KMS11, 8226/S) were treated with either arsenic trioxide (ATO) for 6, 24, or 48 hours or darinaparsin (DAR) for 6 or 24 hours; RNA was extracted from treated and control cells for microarray analysis

我们采用基因芯片（microarrays）技术，检测三氧化二砷（arsenic trioxide）与达林帕辛（darinaparsin）处理多发性骨髓瘤（multiple myeloma）细胞系后，细胞内基因表达的变化情况。
关键词：时间进程（Time course）
实验整体设计：选取4株多发性骨髓瘤细胞系（U266、MM.1s、KMS11、8226/S），分别以三氧化二砷（ATO）处理6、24或48小时，或以达林帕辛（DAR）处理6或24小时；分别从处理组与对照组细胞中提取RNA，用于基因芯片分析。