Fetal ovary expression profile. Fetal ovary expression profile

We sequenced RNA extracted from a 21-weeks gestation human ovary, at the time when dynamic developmental changes occur in human ovarian development and include primordial follicle formation. We examined genes comprised by copy number variants in fertile and POI women for their expression level in ovarian tissue. Overall design: analysis of genes expreesion in fetal ovaries

本研究对孕21周的人类卵巢提取的RNA进行了测序，该阶段是人类卵巢发育发生动态变化且包含原始卵泡形成的关键时期。我们针对可育女性与早发性卵巢功能不全（Premature Ovarian Insufficiency, POI）女性体内由拷贝数变异（Copy Number Variants, CNV）所涵盖的基因，检测其在卵巢组织中的表达水平。整体实验设计：胎儿卵巢的基因表达分析。