DNA methylation differences between Timema cristinae ecotypes. Timema cristinae

We characterize patterns of DNA methylation for natural populations of Timema cristinae adapted to two host plant species (i.e., ecotypes). By integrating results from sequencing of whole transcriptomes, genomes, and methylomes, we investigate whether environmental, host, and genetic differences of these stick insects are associated with methylation levels of cytosine nucleotides in CpG context.

我们对适应两种寄主植物（即生态型）的克里斯蒂娜竹节虫（Timema cristinae）自然种群的DNA甲基化模式进行了表征。通过整合全转录组、全基因组与甲基化组的测序结果，我们探究了这类竹节虫的环境差异、寄主差异及遗传差异是否与CpG二核苷酸背景下的胞嘧啶核苷酸甲基化水平相关。