ATN 052 Monitoring Untoward Effects Form: Actions Taken [CRF 96] Dataset in Population Genetics and Immune Response to Hepatitis B Vaccination in Adolescents: A Substudy of ATN 024 and ATN 025

Dataset with no observations
Study Description
A laboratory-based substudy of ATN 024 and ATN 025 that evaluated the genetic contribution of highly individualized immune responses to the hepatitis B vaccine in individuals. The correlation of specific human leukocyte antigen (HLA) alleles and haplotypes with hepatitis B virus (HBV) antibody concentrations and antibody decay kinetics in vaccinated adolescents was also investigated.
HIV-infected and uninfected youth aged 12 to 24 years

无观测数据的数据集
研究概况
本研究为针对ATN 024与ATN 025的实验室子研究，旨在评估个体内高度个体化的免疫应答对乙型肝炎疫苗的遗传贡献。本研究同时探究了接种乙型肝炎疫苗的青少年中，特定人类白细胞抗原（human leukocyte antigen, HLA）等位基因与单倍型，与乙型肝炎病毒（hepatitis B virus, HBV）抗体浓度及抗体衰减动力学之间的相关性。研究对象为年龄12至24岁的HIV感染与未感染青年群体。