MCF10A EGF induction time-course SUMO2/3 ChIP-seq

starved MCF10A cells were induced and collected for SUMO ChIP-seq. Aim - to assess the effects of stimuli on SUMO recruitment to chromatin. Changes n SUMO binding are evident over time after induction, especially in early response genes.对经饥饿处理的MCF10A细胞进行诱导处理后收集细胞，用于SUMO染色质免疫共沉淀测序（SUMO ChIP-seq）。本研究旨在评估刺激因素对SUMO蛋白招募至染色质的调控作用。诱导处理后，SUMO结合水平随时间推移呈现显著变化，尤其在早期应答基因区域表现尤为突出。