Data Sheet 1_Mechanisms of innate immune cells in Metabolic dysfunction-associated steatotic liver disease.csv

With the continuous increase of the incidence of Metabolic dysfunction-associated steatotic liver disease(MASLD), the proportion of MASLD-driven hepatocellular carcinoma(HCC) is gradually increasing, which will become a heavy burden on global public health. This article summarizes the existing literature and discusses the role of various innate immune cells in the occurrence and development of MASLD, such as cell-cell crosstalk, and uses bibliometric analysis to find current research hotspots and emerging topics, in order to provide valuable reference for scholars studying the direction of MASLD-driven HCC immunity. It also provides a solid foundation for more researchers to join the research direction. And try to inspire researchers in future research to seek breakthroughs in this regard.

随着代谢功能障碍相关脂肪性肝病（Metabolic dysfunction-associated steatotic liver disease, MASLD）发病率的持续攀升，由其驱动的肝细胞癌（hepatocellular carcinoma, HCC）占比亦逐步升高，或将成为全球公共卫生领域的沉重负担。本文系统梳理现有研究文献，探讨各类固有免疫细胞在MASLD发生发展中的作用（包括细胞间串扰等机制），并通过文献计量分析方法挖掘当前研究热点与新兴主题，旨在为研究MASLD驱动型HCC免疫方向的学者提供有价值的参考依据，同时为更多研究者投身该领域研究筑牢基础，并力争为后续相关领域的研究者提供研究突破的思路启发。