Individuals with peripheral vestibulopathy and poor quality of sleep are at a higher risk for falls

Abstract Introduction There is a lack of scientific studies on the assessment of patients with vestibular disorders associated with sleep quality disorders and its impact on the balance and overall quality of life. Objectives to assess the impact of the sleep quality on the balance and quality of life of individuals with peripheral vestibulopathies. Methods 52 individuals with peripheral vestibulopathies underwent sleep quality assessment through the Pittsburgh sleep quality index, neurotological examination through dizziness handicap inventory and Tetrax posturography (Sunlight Medical Ltd.) in eight sensory conditions. Thirty-two healthy individuals (G3) participated as the control group. Results Fourteen individuals with vestibulopathy had good quality of sleep (G1) and 38 showed poor quality of sleep (G2) as demonstrated by the Pittsburgh sleep quality index global scores (p = 0.001). The dizziness handicap inventory showed worse impact of the dizziness on the quality of life in G2 when compared to G1 (p = 0.045). The G2 showed higher risk of falling in posturography when compared to G3 (p = 0.012) and higher index of postural instability in five sensory conditions in comparison with G3. In the vestibulopathy groups, the worse the sleep quality, the higher the risk of falling (r = 0.352) and the worse the quality of life (r = 0.327). Conclusion Individuals with peripheral vestibulopathies and poor quality of sleep demonstrate worse balance evidenced by increased postural instability, higher risk of falls and worse perceived quality of life. The quality of sleep is a predictive factor for worse perceived quality of life and for higher risk of falls in individuals with peripheral vestibulopathies.

摘要 引言 目前针对合并睡眠质量障碍的前庭疾病患者的评估，及其对平衡功能与整体生活质量影响的相关科学研究仍较为匮乏。【研究目的】评估睡眠质量对外周前庭病（peripheral vestibulopathies）患者的平衡功能及生活质量的影响。【研究方法】招募52名外周前庭病患者，采用匹兹堡睡眠质量指数（Pittsburgh Sleep Quality Index）进行睡眠质量评估，通过眩晕残障量表（Dizziness Handicap Inventory）完成神经耳科检查，并借助Tetrax姿势图（Tetrax posturography，Sunlight Medical Ltd.）在8种感觉条件下开展姿势测试。另招募32名健康受试者作为对照组（G3组）。【研究结果】根据匹兹堡睡眠质量指数总分结果，14名前庭病患者睡眠质量良好（G1组），38名患者睡眠质量较差（G2组，p=0.001）。相较于G1组，G2组的眩晕残障量表评分更高，提示眩晕对其生活质量的负面影响更为显著（p=0.045）。与对照组G3相比，G2组的姿势图测试显示跌倒风险更高（p=0.012），且在5种感觉条件下的姿势不稳指数更高。在所有前庭病患者组中，睡眠质量越差，跌倒风险越高（r=0.352），生活质量也越差（r=0.327）。【研究结论】合并睡眠质量较差的外周前庭病患者，其平衡功能受损更严重，具体表现为姿势不稳程度升高、跌倒风险增加以及主观感知的生活质量更差。睡眠质量可作为外周前庭病患者主观生活质量下降及跌倒风险升高的预测因素。