Coagulase negative staphylococci from human skin Genome sequencing and assembly

The genus Staphylococcus is a prominent member of the human skin microbiome, performing diverse functions that are important for immunity, wound repair, and colonization resistance. Each of these functions is carried out by a subset of staphylococcal strains, with strain-level differences in gene content and regulation. Describing this genomic diversity is important for understanding the microbiome's role in human health and disease.

葡萄球菌属（Staphylococcus）是人体皮肤微生物组的重要类群，可执行多种与人体免疫、伤口修复及定植抗力密切相关的功能。上述各项功能均由特定的葡萄球菌菌株亚群介导实现，不同菌株在基因组成与调控机制上存在显著的株级差异。阐明这一基因组多样性，对于理解皮肤微生物组在人类健康与疾病进程中的作用具有重要意义。