Brainstem auditory evoked potentials in smokers

ABSTRACT Purpose: to perform a comparative study of brainstem evoked auditory potentials between smokers and non-smokers. Methods: the group studied was composed of 40 individuals, being 20 non-smokers and 20 smokers within the range of 20 to 59 years of age. All participants had to present responses to tonal thresholds within normal range and tympanometry type A, with the presence of ipsilateral and contralateral acoustic reflexes. Both groups underwent brain stem auditory evoked potential (BAEP). The parameters used to compare the two groups were the absolute latencies of waves I, III and V, the inter-latency waves I-III, IV and III-V in both ears, the difference between the IV inter-peak latency between the two ears and the inter-aural difference of wave V absolute latency between the two ears. Results: in our results, it was ascertained that the group of smokers showed latency I in the RE (p= 0.036), latency V in the RE (p= 0.007), latency V in the LE (p=0.014), inter-latency III-V in the RE (p=0.015) and LE (p= 0.016) significantly higher than the non-smokers. There was no significant difference in wave V latency between the two ears. Conclusion: the results of the study led to the conclusion that tobacco is a risk factor for the central auditory nervous system, interfering with latencies and with BAEP inter-wave latencies in the group of smokers when compared to the group of non-smokers.

## 摘要
目的：开展吸烟者与非吸烟者脑干听觉诱发电位（brainstem evoked auditory potentials）的对比研究。
方法：本研究纳入40名研究对象，年龄范围为20至59岁，其中非吸烟者与吸烟者各20名。所有受试者需满足纯音听阈处于正常范围、鼓室图为A型，且存在同侧及对侧声反射的纳入标准。两组受试者均接受了脑干听觉诱发电位（brain stem auditory evoked potential, BAEP）检测。用于两组对比的参数包括：双耳I、III、V波的绝对潜伏期，双耳I-III、IV、III-V波的峰间期，双耳间IV峰间期差值，以及双耳间V波绝对潜伏期的耳间差。
结果：本研究结果证实，吸烟者组的右侧耳（Right Ear, RE）I波潜伏期（P=0.036）、右侧耳V波潜伏期（P=0.007）、左侧耳（Left Ear, LE）V波潜伏期（P=0.014）、右侧耳III-V峰间期（P=0.015）及左侧耳III-V峰间期（P=0.016）均显著高于非吸烟者组；两组间V波潜伏期的耳间差异无统计学意义。
结论：本研究结果表明，烟草是中枢听觉神经系统的危险因素，与非吸烟者组相比，吸烟者组的潜伏期及BAEP波峰间期均受到烟草的干扰。