Paenibacillus elgii strain:219 Genome sequencing. Paenibacillus elgii strain:219

Paenibacillus elgii 219, a soil microorganism preserved in our laboratory, plays a vital role in the production of numerous well-known compounds, including the lanthipeptide-class peptide penisin and the cyclic lipopeptide octapeptin. These antimicrobials exhibit remarkable biological activity, with a special emphasis on their potential to combat clinically drug-resistant bacterial infections. This unique attribute underscores the immense potential of Paenibacillus elgii 219 as a cell factory.

保藏于本实验室的土壤微生物埃尔吉类芽孢杆菌(Paenibacillus elgii) 219，在多种知名化合物的生物合成中发挥关键作用，其中包括羊毛硫肽(lanthipeptide)类肽类物质penisin以及环脂肽(cyclic lipopeptide)类物质辛肽素(octapeptin)。这类抗菌物质展现出优异的生物活性，尤其在对抗临床耐药细菌感染方面极具应用潜力。这一独特特性凸显了埃尔吉类芽孢杆菌219作为细胞工厂的巨大应用潜力。