Table_1_A Review of Controversial Issues in the Management of Head and Neck Cancer: A Swiss Multidisciplinary and Multi-Institutional Patterns of Care Study—Part 1 (Head and Neck Surgery).XLSX

Background: The Head and Neck Cancer Working Group of Swiss Group for Clinical Cancer Research (SAKK) has investigated the level of consensus (LOC) and discrepancy in everyday practice of diagnosis and treatment in head and neck cancer.
Materials and Methods: An online survey was iteratively generated with 10 Swiss university and teaching hospitals. LOC below 50% was defined as no agreement, while higher LOC were arbitrarily categorized as low (51–74%), moderate (75–84%), and high (≥85%).
Results: Any LOC was achieved in 62% of topics (n = 60). High, moderate and low LOC were found in 18, 20, and 23%, respectively. Regarding Head and Neck Surgery, Radiation Oncology, Medical Oncology, and biomarkers, LOC was achieved in 50, 57, 83, and 43%, respectively.
Conclusions: Consensus on clinical topics is rather low for surgeons and radiation oncologists. The questions discussed might highlight discrepancies, stimulate standardization of practice, and prioritize topics for future clinical research.

背景：瑞士临床癌症研究小组（Swiss Group for Clinical Cancer Research, SAKK）下属头颈癌工作组开展了一项研究，旨在调查头颈癌诊疗日常实践中的共识水平（level of consensus, LOC）与分歧。
材料与方法：研究团队联合10家瑞士大学教学医院，迭代开发了一份在线调查问卷。将共识水平低于50%定义为未达成共识，高于50%的共识水平则被人为划分为低（51%–74%）、中（75%–84%）及高（≥85%）三个等级。
结果：本次研究中，62%的议题（n=60）达成了任一等级的共识。其中高、中、低共识水平的占比分别为18%、20%与23%。针对头颈外科、放射肿瘤学、肿瘤内科及生物标志物相关议题，达成共识的占比分别为50%、57%、83%与43%。
结论：外科医师与放射肿瘤医师针对临床相关议题的共识水平普遍偏低。本次研讨涉及的议题或可凸显当前诊疗实践中的分歧，推动临床诊疗规范的统一，并为未来临床研究的选题优先级提供参考依据。