Effects of different anti-diabetic pharmacotherapies on adipokine serum concentrations.

Comparison of adipokine serum concentrations in patients treated with or without metformin in monotherapy or in combination with GLP-1 analogues and insulin, as well as insulin monotherapy. Only significant differences between the different treatment regimens are displayed. Treatment with sulfonylurea, pioglitazone or DPP-4 inhibitors did not significantly affect serum adipokine concentrations.本数据集对比了接受多种治疗方案的患者的血清脂肪细胞因子（adipokine）浓度，所涉方案包括：使用或不使用二甲双胍（metformin）的单药治疗、联合使用二甲双胍与胰高血糖素样肽-1类似物（GLP-1 analogues）及胰岛素的治疗，以及单纯胰岛素治疗。本数据集仅展示不同治疗方案间存在显著统计学差异的结果。此外，采用磺脲类药物（sulfonylurea）、吡格列酮（pioglitazone）或二肽基肽酶-4抑制剂（DPP-4 inhibitors）进行治疗，并未对患者的血清脂肪细胞因子浓度产生显著影响。