EOS08 Supplemental Data Form, Section E, Treatment Interventions SAS in Early-Onset Sepsis an NICHD/CDC Surveillance Study

EOS08 Supplemental Data Form, Section E, Treatment Interventions
Study Description
This observational study was a surveillance of all infants born at NRN centers to identify all newborns who are diagnosed with early-onset sepsis (EOS) and/or meningitis. The purpose of the study was to establish current hospital-based rates of EOS among term and preterm infants in the era of intrapartum antibiotic prophylaxis; monitor the organisms associated with EOS and meningitis; compare asymptomatic and symptomatic infants by gestational age and pathogen; and monitor sepsis-associated mortality rates by pathogen group. Infants born at NRN centers who are diagnosed with early-onset sepsis (EOS) and/or meningitis.

EOS08 补充数据表 E部分：治疗干预措施
研究概况
本项观察性研究针对新生儿研究网络（Neonatal Research Network, NRN）各中心出生的全部新生儿开展监测，旨在筛查所有被诊断为早发性脓毒症（Early-onset Sepsis, EOS）和/或脑膜炎的新生儿。本研究的核心目标包括：确立产时抗生素预防时代下足月儿与早产儿的院内早发性脓毒症发病现况；监测与早发性脓毒症及脑膜炎相关的病原菌类型；按胎龄与病原菌类型对比无症状与有症状患儿的差异；以及按病原菌分组监测脓毒症相关病死率。本研究的研究对象为新生儿研究网络各中心出生且被诊断为早发性脓毒症（EOS）和/或脑膜炎的新生儿。