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Patients who underwent CBCT at Wonkwang University Daejeon Dental Hospital between January 2019 and December 2022 and were diagnosed with COD and PC by clinical, radiologic, and, if necessary, histopathologic examination were included. Twenty-five patients each were retrospectively enrolled in the COD and PC group. All lesions observed on axial CBCT images were manually segmented using the open-access software MaZda version 4.6 to establish the regions of interest, which were then subjected to texture analysis. Among the 279 texture features obtained, 10 texture features with the highest Fisher coefficients were selected. Statistical analysis was performed using the Mann-Whitney U-test, Welch’s t-test, or Student’s t-test. Texture features that showed significant differences were subjected to receiver operating characteristics (ROC) curve analysis to evaluate the differential diagnostic ability of COD and PC.

本研究纳入2019年1月至2022年12月期间于圆光大学大田牙科医院接受锥形束计算机断层扫描（CBCT），且经临床、影像学检查，必要时结合组织病理学检查确诊为牙骨质骨发育异常（COD）与根尖周牙骨质瘤（PC）的患者，并回顾性纳入两组各25例患者。所有轴位CBCT图像上观测到的病变均通过开放获取软件MaZda 4.6版进行手动分割以划定感兴趣区域，随后对该区域开展纹理分析。在提取得到的279项纹理特征中，筛选出费舍尔系数最高的10项特征。统计分析采用曼-惠特尼U检验、韦尔奇t检验或学生t检验。对存在显著差异的纹理特征开展受试者工作特征曲线（Receiver Operating Characteristics，ROC）分析，以评估COD与PC的鉴别诊断效能。