Systematic evaluation of isoform function in literature reports of alternative splicing

Systematic evaluation of splice isoform function to determine genes with functionally distinct splice isoforms based on experimental evidence. Framework and analysis of curation provided in the above preprint. The data are provided in two parts. First part is the PubMed IDs of all curated studies and their annotations based on our curation framework. Second, are the genes with literature evidence of functionally distinct splice isoforms, and further notes about functional distinctness.

基于实验证据系统性评估剪接异构体（splice isoform）的功能，以鉴定携带功能差异剪接异构体的基因。本数据集的注释框架与分析流程已在上述预印本中详细阐述。数据集包含两部分内容：第一部分为所有经人工注释的研究的PubMed标识符（PubMed ID），以及基于本注释框架生成的对应注释信息；第二部分为存在文献证据支持其剪接异构体存在功能差异的基因，以及关于其功能差异的补充说明。