Supplemental Material for Jain, 2019

All details included in supplemental.tex

Figure S1: Fixation probability for N = 6 × 105 when the beneficial effect sb is varied. The other parameters are sd = 0.01 (top) and 0.002 (bottom) with ud = 5sd, Ud = ud. The data from stochastic simulations (•) with errorbars representing the standard deviation, and by numerically calculating (1) (◦) and (5) (△) are shown.

Figure S2: Fixation probability for N = 6 × 105 when the beneficial effect sb is varied. The other parameters are sd = 0.01, ud = 5sd, Ud = 2ud (top) and sd = 0.002, ud = 5sd, Ud = 5ud (bottom). The data from stochastic simulations (•) with errorbars representing the standard deviation, and by numerically calculating (1) (◦) and (5) (△) are shown.

Figure S3: Expected substitution rate E[kb] and average fixed selection co-efficient E[sb] for N = 2 × 105 when the average beneficial effect s¯b is varied. The other parameters are sd = 0.01, ud = 5sd, ub = 5 × 10−7. The data from numerical simulations (•) and numerical integration of (12) and (17) using quadratic approximation (5) (⊕) and analytical expression (9) (◦) are shown.

所有详细内容均收录于supplemental.tex文件中。

图S1：当有益效应参数$s_b$变化时，种群规模$N=6 imes10^5$下的固定概率。其余参数设置为：$s_d=0.01$（上图）与$0.002$（下图），且满足$u_d=5s_d$、$U_d=u_d$。本图展示了随机模拟得到的数据（以•标记，误差棒代表标准差），以及通过数值计算式(1)（以◦标记）和式(5)（以△标记）得到的结果。

图S2：当有益效应参数$s_b$变化时，种群规模$N=6 imes10^5$下的固定概率。其余参数设置为：上图为$s_d=0.01$、$u_d=5s_d$、$U_d=2u_d$；下图为$s_d=0.002$、$u_d=5s_d$、$U_d=5u_d$。本图展示了随机模拟得到的数据（以•标记，误差棒代表标准差），以及通过数值计算式(1)（以◦标记）和式(5)（以△标记）得到的结果。

图S3：当平均有益效应参数$overline{s}_b$变化时，种群规模$N=2 imes10^5$下的预期替换率$E[k_b]$与平均固定选择系数$E[s_b]$。其余参数设置为：$s_d=0.01$、$u_d=5s_d$、$u_b=5 imes10^{-7}$。本图展示了数值模拟得到的数据（以•标记），以及通过二次近似式(5)对式(12)和式(17)进行数值积分得到的结果（以⊕标记），还有解析表达式(9)得到的结果（以◦标记）。