PD1 signaling network, discovery dataset 1

Cytoscape file to reproduce the network representation of differential gene regulation in the PD1 signaling pathway in discovery dataset 1, as described in our manuscript "Regulation of PD1 signaling is associated with prognosis in glioblastoma multiforme." Node size corresponds to the number of edges connected in the graph; line-width of edges corresponds to their signi cance in di erential regulation. Gene targeting scores (or "degrees") are shown with a circle surrounding the node. Red: higher expression/targeting in short-term survivors,<br> blue: higher expression/targeting in the long-term survivors.

本研究手稿《PD1信号通路调控与多形性胶质母细胞瘤预后相关（"Regulation of PD1 signaling is associated with prognosis in glioblastoma multiforme"）》中所述的发现数据集1内，用于复现PD1（Programmed Death 1）信号通路差异基因调控网络可视化结果的Cytoscape软件（Cytoscape）文件。节点尺寸对应于图中连接的边数；边的线宽代表其在差异调控中的显著性。基因靶向评分（或称“度值”）以环绕节点的圆形标记展示。红色代表短期存活者中更高的表达或靶向水平，蓝色代表长期存活者中更高的表达或靶向水平。