Rxrg

Enables nuclear receptor activity and sequence-specific DNA binding activity. Acts upstream of or within positive regulation of transcription by RNA polymerase II and retinoic acid receptor signaling pathway. Predicted to be located in cytoplasm and nucleus. Predicted to be part of RNA polymerase II transcription regulator complex. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; musculature; and sensory organ. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma. Orthologous to human RXRG (retinoid X receptor gamma). [provided by Alliance of Genome Resources, Nov 2024]

此基因激活核受体活性及序列特异性DNA结合活性。其在RNA聚合酶II转录的正调控及视黄酸受体信号通路中发挥上游或内部作用。预测其定位于细胞质和细胞核。预测其为RNA聚合酶II转录调节复合体的一部分。在多个结构中表达，包括消化系统、中枢神经系统、泌尿生殖系统、肌肉组织和感觉器官。该基因的人类同源基因与肺非小细胞癌有关。与人类RXRG（视黄酸X受体gamma）同源。[由基因组资源联盟提供，2024年11月]