Malignant neoplasm of testis - Male, 27 - Tissue image [6080730009646391]

This is the histopathological image of TESTIS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 27Clinical description: Tumour of the left testicleGender: MaleDiagnosis:Classification: ICD-10_10-20Classification code: Chapter II - NeoplasmsDiagnosis: Malignant neoplasm of testisResult of the histopathological examination: Mixed testicular germ cell tumor, which includes seminoma, germ cell carcinoma and yolk sac tumor. Diffuse intratubular germ cell neoplasia in the adjacent parenchyma. Seminoma accounts for approximately 60% of malignant uterus, 35% of germ cell carcinoma and 5% of yolk sac tumour. Germ cell carcinoma with areas of extensive necrosis (about 70-80% of its tissue).
The seminoma focally infiltrates the testicle network. The tumor is confined to the testicle parenchyma and does not infiltrate the lining.
Vascular invasion has not been identified.
IHC: seminoma-OCT 3/4 (+), germ cell carcinoma -OCT 3/4 (+), CD 30 (+), beta HCG (-), Glipican 3 (-), AFP (-), yolk sac tumor -AFP (+), Glipican 3 (+).Sample:Material: FFPECollecting method: Surgical specimenTopography: MALE GENITAL ORGANSOrgan: TESTISTissue: Testis, NOSType of staining: positive/HEStaining: Not applicableAntibody: Not applicableTechnology:Equipment: Pannoramic 250 3DHistechLens: 20xOrganization:Source: Medical University Gdańsk

本数据集为格但斯克医科大学（Medical University Gdańsk）获取并存储于ZMDL-GUMED数据库的睾丸组织样本组织病理学图像。该样本图像采用Pannoramic 250 3DHistech玻片扫描仪（20倍放大倍率）采集，并以DICOM格式存储。

患者、样本及诊断相关详细信息如下：
患者：
年龄：27岁
临床描述：左侧睾丸肿瘤
性别：男性
诊断分类：ICD-10_10-20，分类编码为第二章——肿瘤（Chapter II - Neoplasms）
诊断结果：睾丸恶性肿瘤
组织病理学检查结果：混合性睾丸生殖细胞肿瘤，包含精原细胞瘤（seminoma）、生殖细胞癌（germ cell carcinoma）及卵黄囊瘤（yolk sac tumor）；邻近实质组织可见弥漫性曲细精管内生殖细胞肿瘤变。精原细胞瘤约占子宫恶性肿瘤的60%、生殖细胞癌的35%及卵黄囊瘤的5%。生殖细胞癌存在大面积坏死区域，约占其组织总量的70%~80%。
精原细胞瘤局灶性浸润睾丸网；肿瘤局限于睾丸实质内，未浸润被膜。未检测到血管浸润。
免疫组化（IHC，Immunohistochemistry）结果：精原细胞瘤-OCT 3/4（+）、生殖细胞癌-OCT 3/4（+）、CD30（+）、β-HCG（-）、Glipican 3（-）、AFP（-）；卵黄囊瘤-AFP（+）、Glipican 3（+）。

样本相关信息：
样本材料：FFPE（福尔马林固定石蜡包埋组织，Formalin-Fixed Paraffin-Embedded）
采集方式：手术标本
部位：男性生殖器官
器官：睾丸
组织类型：睾丸，NOS（未特指类型，Not Otherwise Specified）
染色类型：阳性/HE染色
染色方式：无特殊要求
所用抗体：未使用特异性抗体
技术与设备：
设备：Pannoramic 250 3DHistech
物镜倍率：20倍
来源机构：格但斯克医科大学